Pancreatic Damage in Fetal and Newborn Cystic Fibrosis Pigs Involves the Activation of Inflammatory and Remodeling Pathways

Pancreatic disease has onset in utero in humans with cystic fibrosis (CF), and progresses over time to complete destruction of the organ. The exact mechanisms leading to pancreatic damage in CF are incompletely understood. Inflammatory cells are present in the pancreas of newborn pigs with CF (CF pi...

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Autors principals: Abu-El-Haija, Maisam, Ramachandran, Shyam, Meyerholz, David K., Abu-El-Haija, Marwa, Griffin, Michelle, Giriyappa, Radhamma L., Stoltz, David A., Welsh, Michael J., McCray, Paul B., Uc, Aliye
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2012
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409440/
https://ncbi.nlm.nih.gov/pubmed/22683312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.04.024
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