Pancreatic Damage in Fetal and Newborn Cystic Fibrosis Pigs Involves the Activation of Inflammatory and Remodeling Pathways

Pancreatic disease has onset in utero in humans with cystic fibrosis (CF), and progresses over time to complete destruction of the organ. The exact mechanisms leading to pancreatic damage in CF are incompletely understood. Inflammatory cells are present in the pancreas of newborn pigs with CF (CF pi...

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Main Authors: Abu-El-Haija, Maisam, Ramachandran, Shyam, Meyerholz, David K., Abu-El-Haija, Marwa, Griffin, Michelle, Giriyappa, Radhamma L., Stoltz, David A., Welsh, Michael J., McCray, Paul B., Uc, Aliye
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2012
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409440/
https://ncbi.nlm.nih.gov/pubmed/22683312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.04.024
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