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Germline copy number variants are not associated with globally acquired copy number changes in familial breast tumours

A characteristic of sporadic and familial breast tumours is genomic instability, resulting from either inherited mutations in genes that control genome integrity or mutations that are acquired in somatic cells during development. It is well established that abnormal chromosome number and structural...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Walker, Logan C., Krause, Lutz, Spurdle, Amanda B., Waddell, Nic
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409366/
https://ncbi.nlm.nih.gov/pubmed/22434526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2024-6
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