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Germline copy number variants are not associated with globally acquired copy number changes in familial breast tumours

A characteristic of sporadic and familial breast tumours is genomic instability, resulting from either inherited mutations in genes that control genome integrity or mutations that are acquired in somatic cells during development. It is well established that abnormal chromosome number and structural...

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Autors principals: Walker, Logan C., Krause, Lutz, Spurdle, Amanda B., Waddell, Nic
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409366/
https://ncbi.nlm.nih.gov/pubmed/22434526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2024-6
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