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Germline copy number variants are not associated with globally acquired copy number changes in familial breast tumours

A characteristic of sporadic and familial breast tumours is genomic instability, resulting from either inherited mutations in genes that control genome integrity or mutations that are acquired in somatic cells during development. It is well established that abnormal chromosome number and structural...

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Bibliographic Details
Main Authors: Walker, Logan C., Krause, Lutz, Spurdle, Amanda B., Waddell, Nic
Format: Artigo
Language:Inglês
Published: Springer US 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409366/
https://ncbi.nlm.nih.gov/pubmed/22434526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2024-6
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