Regulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A(2)-IIA in microvascular endothelial cells of the injured brain

BACKGROUND: Secreted phospholipase A(2)-IIA (sPLA(2)-IIA) is an inducible enzyme released under several inflammatory conditions. It has been shown that sPLA(2)-IIA is released from rat brain astrocytes after inflammatory stimulus, and lipopolysaccharide (LPS) and nitric oxide (NO) have been implicat...

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Detalhes bibliográficos
Main Authors: Wang, Guansong, Qian, Pin, Xu, Zhi, Zhang, Jiqiang, Wang, Yaoli, Cheng, Saiyu, Cai, Wenqin, Qian, Guisheng, Wang, Changzheng, DeCoster, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409030/
https://ncbi.nlm.nih.gov/pubmed/22788969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-170
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