Regulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A(2)-IIA in microvascular endothelial cells of the injured brain

BACKGROUND: Secreted phospholipase A(2)-IIA (sPLA(2)-IIA) is an inducible enzyme released under several inflammatory conditions. It has been shown that sPLA(2)-IIA is released from rat brain astrocytes after inflammatory stimulus, and lipopolysaccharide (LPS) and nitric oxide (NO) have been implicat...

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Bibliografiske detaljer
Main Authors:	Wang, Guansong, Qian, Pin, Xu, Zhi, Zhang, Jiqiang, Wang, Yaoli, Cheng, Saiyu, Cai, Wenqin, Qian, Guisheng, Wang, Changzheng, DeCoster, Mark A
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2012
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3409030/ https://ncbi.nlm.nih.gov/pubmed/22788969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-170
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Regulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A(2)-IIA in microvascular endothelial cells of the injured brain

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