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Human Mut T homolog 1 (MTH1): A roadblock for the tumor-suppressive effects of oncogenic RAS-induced ROS

Oncogenic RAS-induced reactive oxygen species (ROS) trigger barriers to cell transformation and cancer progression through tumor-suppressive responses such as cellular senescence or cell death. We have recently shown that oncogenic RAS-induced DNA damage and attendant premature senescence can be pre...

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Bibliografske podrobnosti
Glavni avtor: Rai, Priyamvada
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408976/
https://ncbi.nlm.nih.gov/pubmed/22790201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.19556
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