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Activation of NMDA receptors leads to phosphorylation of TRPV1 S800 by protein kinase C and A-Kinase anchoring protein 150 in rat trigeminal ganglia

A-Kinase anchoring protein 150 (AKAP150) is required for the phosphorylation of transient receptor potential cation channel subfamily V member 1 (TRPV1) by PKA or PKC in sensory neurons and, hence, affects TRPV1-dependent hyperalgesia under pathological conditions. Recently, we showed that the activ...

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Autors principals: Lee, Jongseok, Chung, Man-Kyo, Ro, Jin Y
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408820/
https://ncbi.nlm.nih.gov/pubmed/22789851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.07.008
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