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Peripheral Group I metabotropic glutamate receptor activation leads to muscle mechanical hyperalgesia through TRPV1 phosphorylation in the rat

Elevated glutamate levels within injured muscle play important roles in muscle pain and hyperalgesia. In this study, we hypothesized that PKC-dependent TRPV1 phosphorylation contributes to the muscle mechanical hyperalgesia following activation of Group I metabotropic glutamate receptors (mGlu1/5)....

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Detalhes bibliográficos
Publicado no:J Pain
Main Authors: Chung, Man-Kyo, Lee, Jongseok, Joseph, John, Saloman, Jami, Ro, Jin Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274191/
https://ncbi.nlm.nih.gov/pubmed/25451626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2014.10.008
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