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A Model of Nitric Oxide Induced α-Synuclein Misfolding in Parkinson’s Disease

Inducible nitric oxide synthase (iNOS) upregulation and consequent NO formation are well-recognized neuroinflammatory responses associated with Parkinson’s disease (PD). These contribute to nitrosative protein modifications affecting neuronal injury and cell death. Indeed, a pathobiologic signature...

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Detalhes bibliográficos
Main Authors: Stone, David K., Kiyota, Tomomi, Mosley, R. Lee, Gendelman, Howard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408780/
https://ncbi.nlm.nih.gov/pubmed/22776646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.06.070
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