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OXIDANTS INDUCE ALTERNATIVE SPLICING OF α-SYNUCLEIN: IMPLICATIONS FOR PARKINSON’S DISEASE
α-Synuclein (α-syn) is a presynaptic protein that is widely implicated in the pathophysiology of Parkinson’s disease (PD). Emerging evidence indicates a strong correlation between α-syn aggregation and proteasomal dysfunction as one of the major pathways responsible for destruction of the dopamine n...
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| Publicado no: | Free Radic Biol Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485429/ https://ncbi.nlm.nih.gov/pubmed/19857570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.10.045 |
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