OXIDANTS INDUCE ALTERNATIVE SPLICING OF α-SYNUCLEIN: IMPLICATIONS FOR PARKINSON’S DISEASE

α-Synuclein (α-syn) is a presynaptic protein that is widely implicated in the pathophysiology of Parkinson’s disease (PD). Emerging evidence indicates a strong correlation between α-syn aggregation and proteasomal dysfunction as one of the major pathways responsible for destruction of the dopamine n...

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Bibliographic Details
Published in:Free Radic Biol Med
Main Authors: Kalivendi, Shasi V., Yedlapudi, Deepthi, Hillard, Cecilia J., Kalyanaraman, B.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485429/
https://ncbi.nlm.nih.gov/pubmed/19857570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.10.045
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