MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

MicroRNA-122 (miR-122), which accounts for 70% of the liver’s total miRNAs, plays a pivotal role in the liver. However, its intrinsic physiological roles remain largely undetermined. We demonstrated that mice lacking the gene encoding miR-122a (Mir122a) are viable but develop temporally controlled s...

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Detalhes bibliográficos
Main Authors: Tsai, Wei-Chih, Hsu, Sheng-Da, Hsu, Chu-Sui, Lai, Tsung-Ching, Chen, Shu-Jen, Shen, Roger, Huang, Yi, Chen, Hua-Chien, Lee, Chien-Hsin, Tsai, Ting-Fen, Hsu, Ming-Ta, Wu, Jaw-Ching, Huang, Hsien-Da, Shiao, Ming-Shi, Hsiao, Michael, Tsou, Ann-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408747/
https://ncbi.nlm.nih.gov/pubmed/22820290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63455
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