LRH-1–dependent glucose sensing determines intermediary metabolism in liver

Liver receptor homolog 1 (LRH-1), an established regulator of cholesterol and bile acid homeostasis, has recently emerged as a potential drug target for liver disease. Although LRH-1 activation may protect the liver against diet-induced steatosis and insulin resistance, little is known about how LRH...

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Hlavní autoři: Oosterveer, Maaike H., Mataki, Chikage, Yamamoto, Hiroyasu, Harach, Taoufiq, Moullan, Norman, van Dijk, Theo H., Ayuso, Eduard, Bosch, Fatima, Postic, Catherine, Groen, Albert K., Auwerx, Johan, Schoonjans, Kristina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408738/
https://ncbi.nlm.nih.gov/pubmed/22772466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62368
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