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Cyclocreatine treatment improves cognition in mice with creatine transporter deficiency
The second-largest cause of X-linked mental retardation is a deficiency in creatine transporter (CRT; encoded by SLC6A8), which leads to speech and language disorders with severe cognitive impairment. This syndrome, caused by the absence of creatine in the brain, is currently untreatable because CRT...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408730/ https://ncbi.nlm.nih.gov/pubmed/22751104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59373 |
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