Cyclocreatine treatment improves cognition in mice with creatine transporter deficiency

The second-largest cause of X-linked mental retardation is a deficiency in creatine transporter (CRT; encoded by SLC6A8), which leads to speech and language disorders with severe cognitive impairment. This syndrome, caused by the absence of creatine in the brain, is currently untreatable because CRT...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kurosawa, Yuko, DeGrauw, Ton J., Lindquist, Diana M., Blanco, Victor M., Pyne-Geithman, Gail J., Daikoku, Takiko, Chambers, James B., Benoit, Stephen C., Clark, Joseph F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408730/
https://ncbi.nlm.nih.gov/pubmed/22751104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59373
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