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Mutation hotspots in yeast caused by long-range clustering of homopolymeric sequences
Evolutionary theory assumes that mutations occur randomly in the genome; however, studies performed in a variety of organisms indicate the existence of context-dependent mutation biases. Sources of mutagenesis variation across large genomic contexts (e.g. hundreds of bases) have not been identified....
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408629/ https://ncbi.nlm.nih.gov/pubmed/22832106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2011.10.003 |
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