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Structure Activity Relationship of Uridine 5′-Diphosphoglucose (UDP-Glucose) Analogues as Agonists of the Human P2Y(14) Receptor
UDP-glucose (UDPG) and derivatives are naturally-occurring agonists of the G(i) protein-coupled P2Y(14) receptor, which occurs in the immune system. We synthesized and characterized pharmacologically novel analogues of UDPG modified on the nucleobase, ribose, and glucose moieties, as the basis for d...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2007
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408610/ https://ncbi.nlm.nih.gov/pubmed/17407275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm061222w |
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