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Human P2Y(14) Receptor Agonists: Truncation of the Hexose Moiety of Uridine-5′-Diphosphoglucose and its Replacement with Alkyl and Aryl Groups
Uridine-5′-diphosphoglucose (UDPG) activates the P2Y(14) receptor, a neuroimmune system GPCR. P2Y(14) receptor tolerates glucose substitution with small alkyl or aryl groups or its truncation to uridine-5′-diphosphate (UDP), a full agonist human P2Y(14) receptor expressed in HEK-293 cells. 2-Thioura...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804908/ https://ncbi.nlm.nih.gov/pubmed/19902968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901432g |
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