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Triplatin, a platelet aggregation inhibitor from the salivary gland of the triatomine vector of Chagas Disease, binds to TXA(2) but does not interact with GPVI
Salivary glands from hematophagous animals express a notable diversity of negative modulators of platelet function. Triplatin is an inhibitor of collagen-induced platelet aggregation which has been described as an antagonist of glycoprotein VI (GPVI). Because triplatin displays sequence homology to...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408606/ https://ncbi.nlm.nih.gov/pubmed/22159626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH11-10-0685 |
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