Salivary Antigen-5/CAP Family Members Are Cu(2+)-dependent Antioxidant Enzymes That Scavenge O(2)(⨪) and Inhibit Collagen-induced Platelet Aggregation and Neutrophil Oxidative Burst

The function of the antigen-5/CAP family of proteins found in the salivary gland of bloodsucking animals has remained elusive for decades. Antigen-5 members from the hematophagous insects Dipetalogaster maxima (DMAV) and Triatoma infestans (TIAV) were expressed and discovered to attenuate platelet a...

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Detalhes bibliográficos
Main Authors: Assumpção, Teresa C. F., Ma, Dongying, Schwarz, Alexandra, Reiter, Karine, Santana, Jaime M., Andersen, John F., Ribeiro, José M. C., Nardone, Glenn, Yu, Lee L., Francischetti, Ivo M. B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656290/
https://ncbi.nlm.nih.gov/pubmed/23564450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466995
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