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Triplatin, a platelet aggregation inhibitor from the salivary gland of the triatomine vector of Chagas Disease, binds to TXA(2) but does not interact with GPVI

Salivary glands from hematophagous animals express a notable diversity of negative modulators of platelet function. Triplatin is an inhibitor of collagen-induced platelet aggregation which has been described as an antagonist of glycoprotein VI (GPVI). Because triplatin displays sequence homology to...

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Autors principals: Ma, Dongying, Assumpção, Teresa C. F., Li, Yuan, Andersen, John F., Ribeiro, José M.C., Francischetti, Ivo M.B.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408606/
https://ncbi.nlm.nih.gov/pubmed/22159626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH11-10-0685
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