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Selective activation of cholinergic interneurons enhances accumbal phasic dopamine release: setting the tone for reward processing

Dopamine (DA) plays a critical role in motor control, addiction and reward-seeking behaviors, and its release dynamics have traditionally been linked to changes in midbrain dopamine neuron activity. Here, we report that selective endogenous cholinergic activation achieved via in vitro optogenetic st...

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Detalhes bibliográficos
Main Authors: Cachope, Roger, Mateo, Yolanda, Mathur, Brian N., Irving, James, Wang, Hui-Ling, Morales, Marisela, Lovinger, David M., Cheer, Joseph F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408582/
https://ncbi.nlm.nih.gov/pubmed/22840394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.05.011
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