Selective Activation of Cholinergic Interneurons Enhances Accumbal Phasic Dopamine Release: Setting the Tone for Reward Processing

Dopamine plays a critical role in motor control, addiction, and reward-seeking behaviors, and its release dynamics have traditionally been linked to changes in midbrain dopamine neuron activity. Here, we report that selective endogenous cholinergic activation achieved via in vitro optogenetic stimul...

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Hlavní autoři: Roger Cachope, Yolanda Mateo, Brian N. Mathur, James Irving, Hui-Ling Wang, Marisela Morales, David M. Lovinger, Joseph F. Cheer
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2012-07-01
Edice:Cell Reports
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2211124712001362
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