Selective Cytotoxicity of Amidinopiperidine Based Compounds Towards Burkitt’s Lymphoma Cells Involves Proteasome Inhibition

Serine proteases have proven to be promising pharmacological targets in contemporary drug discovery for cancer treatment. Since azaphenylalanine-based compounds manifest cytotoxic activity, we have selected serine protease inhibitors designed and synthesized in-house with large hydrophobic naphthale...

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Detalhes bibliográficos
Main Authors: Gobec, Martina, Obreza, Ales, Prijatelj, Matevz, Brus, Boris, Gobec, Stanislav, Mlinaric-Rascan, Irena
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408433/
https://ncbi.nlm.nih.gov/pubmed/22860040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041961
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