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A Putative Serine Protease is Required to Initiate the RIPK3-MLKL—Mediated Necroptotic Death Pathway in Neutrophils

Adhesion receptors, such as CD44, have been shown to activate receptor interacting protein kinase-3 (RIPK3)—mixed lineage kinase-like (MLKL) signaling, leading to a non-apoptotic cell death in human granulocyte/macrophage colony-stimulating factor (GM-CSF) – primed neutrophils. The signaling events...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wang, Xiaoliang, Avsec, Damjan, Obreza, Aleš, Yousefi, Shida, Mlinarič-Raščan, Irena, Simon, Hans-Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860068/
https://ncbi.nlm.nih.gov/pubmed/33551816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.614928
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