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A focused structure–activity relationship study of psoralen-based immunoproteasome inhibitors

The immunoproteasome is a multicatalytic protease that is predominantly expressed in cells of hematopoietic origin. Its elevated expression has been associated with autoimmune diseases, various types of cancer, and inflammatory diseases. The development of immunoproteasome-selective inhibitors with...

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Publicado en:Medchemcomm
Main Authors: Schiffrer, Eva Shannon, Sosič, Izidor, Šterman, Andrej, Mravljak, Janez, Raščan, Irena Mlinarič, Gobec, Stanislav, Gobec, Martina
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478164/
https://ncbi.nlm.nih.gov/pubmed/32952997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00365g
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