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Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors

The immunoproteasome is a multicatalytic protease that is predominantly expressed in cells of hematopoietic origin. Its elevated expression has been associated with autoimmune diseases, various types of cancer, and inflammatory diseases. Selective inhibition of its catalytic activities is therefore...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Schiffrer, Eva Shannon, Proj, Matic, Gobec, Martina, Rejc, Luka, Šterman, Andrej, Mravljak, Janez, Gobec, Stanislav, Sosič, Izidor
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826781/
https://ncbi.nlm.nih.gov/pubmed/33445542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26020356
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