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Small Molecule-Assisted, Line-Independent Maintenance of Human Pluripotent Stem Cells in Defined Conditions

Human pluripotent stem cells (hPSCs) are conventionally grown in a mouse feeder cell-dependent manner. Chemically defined culture conditions are, however, desirable not only for potential medically oriented applications but also for investigating mechanisms of self-renewal and differentiation. In li...

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Main Authors: Frank, Stefan, Zhang, Miao, Schöler, Hans R., Greber, Boris
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408405/
https://ncbi.nlm.nih.gov/pubmed/22860038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041958
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