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A modified TALEN-based system for robust generation of knock-out human pluripotent stem cell lines and disease models
BACKGROUND: Transcription activator-like effector nucleases (TALENs) have emerged as a tool for enabling targeted gene editing and disruption in difficult systems, such as human pluripotent stem cells (hPSCs). The modular architecture of TAL effectors theoretically enables targeting of any genomic l...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840567/ https://ncbi.nlm.nih.gov/pubmed/24206569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-773 |
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