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DNase I Hypersensitive Site II of the Human Growth Hormone Locus Control Region Mediates an Essential and Distinct Long-range Enhancer Function

Locus control regions (LCRs) comprise sets of DNA elements capable of establishing autonomous chromatin domains that support robust and physiologically appropriate expression of target genes, often working over extensive distances. Human growth hormone (hGH-N) expression in the pituitary is under th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fleetwood, Margaret R., Ho, Yugong, Cooke, Nancy E., Liebhaber, Stephen A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408159/
https://ncbi.nlm.nih.gov/pubmed/22669946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365825
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