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The Protein Zfand5 Binds and Stabilizes mRNAs with AU-rich Elements in Their 3′-Untranslated Regions

AU-rich elements (AREs) in the 3′-UTR of unstable transcripts play a vital role in the regulation of many inflammatory mediators. To identify novel ARE-dependent gene regulators, we screened a human leukocyte cDNA library for candidates that enhanced the activity of a luciferase reporter bearing the...

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Bibliografiske detaljer
Main Authors: He, Guoan, Sun, Dongxu, Ou, Zhiying, Ding, Aihao
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408148/
https://ncbi.nlm.nih.gov/pubmed/22665488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362020
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