SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial–mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway

In our previous study, we found that blockade of SDF-1/CXCR4 signaling inhibits pancreatic cancer cell migration and invasion in vitro. However, the mechanism governing the downstream regulation of SDF-1/CXCR4-mediated invasion remains unclear. Here we report the role of SDF-1/CXCR4 in pancreatic ca...

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Hauptverfasser: Li, Xuqi, Ma, Qingyong, Xu, Qinhong, Liu, Han, Lei, Jianjun, Duan, Wanxing, Bhat, Kruttika, Wang, Fengfei, Wu, Erxi, Wang, Zheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408048/
https://ncbi.nlm.nih.gov/pubmed/22450749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.02.035
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