Role of reactive oxygen species in the synergistic cytotoxicity of safingol-based combination regimens with conventional chemotherapeutics

Exploiting the sensitivity of cancer cells to reactive oxygen species (ROS) has been suggested as a strategy for the selective elimination of cancer cells. In this study, the ROS-generating sphingolipid safingol was combined with various conventional chemotherapeutics, and the potential synergism of...

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Autores principales: Ling, Leong-Uung, Tan, Kuan-Boone, Chiu, Gigi N.C.
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408041/
https://ncbi.nlm.nih.gov/pubmed/22866148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.330
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