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Ferrocenes as potential chemotherapeutic drugs: Synthesis, cytotoxic activity, reactive oxygen species production and micronucleus assay

Three new ferrocene complexes were synthesized with 4-(1H-pyrrol-1-yl)phenol group appended to one of the Cp ring. These are: 1,1′-4-(1H-pyrrol-1-yl)phenyl ferrocenedicarboxylate, (“Fc-(CO(2)-Ph-4-Py)(2)”), 1,4-(1H-pyrrol-1-yl)phenyl, 1′-carboxyl ferrocenecarboxylate (“Fc-(CO(2)-Ph-4-Py)CO(2)H”) and...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Pérez, Wanda I., Soto, Yarelys, Ortíz, Carmen, Matta, Jaime, Meléndez, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330091/
https://ncbi.nlm.nih.gov/pubmed/25555734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.12.023
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