Proline-Rich Tyrosine Kinase 2 (Pyk2) Regulates IGF-I-Induced Cell Motility and Invasion of Urothelial Carcinoma Cells

The insulin-like growth factor receptor I (IGF-IR) plays an essential role in transformation by promoting cell growth and protecting cancer cells from apoptosis. We have recently demonstrated that the IGF-IR is overexpressed in invasive bladder cancer tissues and promotes motility and invasion of ur...

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Main Authors: Genua, Marco, Xu, Shi-Qiong, Buraschi, Simone, Peiper, Stephen C., Gomella, Leonard G., Belfiore, Antonino, Iozzo, Renato V., Morrione, Andrea
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408023/
https://ncbi.nlm.nih.gov/pubmed/22859931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040148
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