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Rapid Access to Chroman-3-Ones via Gold-Catalyzed Oxidation of Propargyl Aryl Ethers

ONLY TWO STEPS? Chroman-3-ones are important intermediates for organic synthesis and medicinal chemistry. However, their syntheses require multiple steps and are not efficient. By using gold-catalyzed alkyne oxidation, this versatile heterocycle can be prepared in only two steps from readily availab...

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Bibliographic Details
Main Authors: Wang, Yanzhao, Ji, Kegong, Lan, Sylvester, Zhang, Liming
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407818/
https://ncbi.nlm.nih.gov/pubmed/22246680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201107561
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