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Transition-Metal Catalyzed Synthesis of Aspergillide B: An Alkyne Addition Strategy

[Image: see text] A catalytic enantioselective formal total synthesis of aspergillide B is reported. This linchpin synthesis was enabled by the development of new conditions for Zn-ProPhenol catalyzed asymmetric alkyne addition. This reaction was used in conjunction with ruthenium-catalyzed trans-hy...

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Détails bibliographiques
Auteurs principaux: Trost, Barry M., Bartlett, Mark J.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407809/
https://ncbi.nlm.nih.gov/pubmed/22356535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300200m
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