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Evaluating Transition-Metal Catalyzed Transformations for the Synthesis of Laulimalide
Laulimalide is a structurally unique 20-membered marine macrolide displaying microtubule stabilizing activity similar to that of paclitaxel and the epothilones. The use of atom economical transformations such as a rhodium-catalyzed cycloisomerization to form the endocyclic dihydropyran, a dinuclear...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791108/ https://ncbi.nlm.nih.gov/pubmed/19891433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja907924j |
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