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Direct interaction between GluR2 and GAPDH regulates AMPAR-mediated excitotoxicity

Over-activation of AMPARs (α−amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptors) is implicated in excitotoxic neuronal death associated with acute brain insults, such as ischemic stroke. However, the specific molecular mechanism by which AMPARs, especially the calcium-imp...

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Detalhes bibliográficos
Main Authors: Wang, Min, Li, Shupeng, Zhang, Hongyu, Pei, Lin, Zou, Shengwei, Lee, Frank J S, Wang, Yu Tian, Liu, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407747/
https://ncbi.nlm.nih.gov/pubmed/22537872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-5-13
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