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Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity

Influx of Ca(2+) ions through α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors contributes to neuronal damage in stroke, epilepsy, and neurodegenerative disorders such as ALS. The Ca(2+) permeability of AMPA receptors is largely determined by the glutamate receptor 2 (GluR2) sub...

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書誌詳細
主要な著者: Van Damme, Philip, Bogaert, Elke, Dewil, Maarten, Hersmus, Nicole, Kiraly, Dora, Scheveneels, Wendy, Bockx, Ilse, Braeken, Dries, Verpoorten, Nathalie, Verhoeven, Kristien, Timmerman, Vincent, Herijgers, Paul, Callewaert, Geert, Carmeliet, Peter, Van Den Bosch, Ludo, Robberecht, Wim
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976195/
https://ncbi.nlm.nih.gov/pubmed/17804792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705046104
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