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NPM-ALK: The Prototypic Member of a Family of Oncogenic Fusion Tyrosine Kinases
Anaplastic lymphoma kinase (ALK) was first identified in 1994 with the discovery that the gene encoding for this kinase was involved in the t(2;5)(p23;q35) chromosomal translocation observed in a subset of anaplastic large cell lymphoma (ALCL). The NPM-ALK fusion protein generated by this translocat...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Hindawi Publishing Corporation
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407651/ https://ncbi.nlm.nih.gov/pubmed/22852078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/123253 |
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