NPM-ALK: The Prototypic Member of a Family of Oncogenic Fusion Tyrosine Kinases

Anaplastic lymphoma kinase (ALK) was first identified in 1994 with the discovery that the gene encoding for this kinase was involved in the t(2;5)(p23;q35) chromosomal translocation observed in a subset of anaplastic large cell lymphoma (ALCL). The NPM-ALK fusion protein generated by this translocat...

Full description

Saved in:
Bibliographic Details
Main Authors: Pearson, Joel D., Lee, Jason K. H., Bacani, Julinor T. C., Lai, Raymond, Ingham, Robert J.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407651/
https://ncbi.nlm.nih.gov/pubmed/22852078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/123253
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items