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PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium
BACKGROUND: Planar Cell Polarity (PCP) signaling is a key regulator of epithelial morphogenesis, including neural tube closure and the orientation of inner ear sensory hair cells, and is mediated by a conserved noncanonical Wnt pathway. Ptk7 is a novel vertebrate-specific regulator of PCP, yet the m...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407606/ https://ncbi.nlm.nih.gov/pubmed/22560610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.03.068 |
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