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The crystal structure of the DNA-binding drug berenil: molecular modelling studies of berenil-DNA complexes.

The crystal structure of the DNA minor-groove DNA-binding drug berenil has been determined. Molecular-modelling techniques have been used to establish plausible binding modes of the structure to A-T sequences. These have shown that specific hydrogen bonds are possible between the amidine groups of t...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Pearl, L H, Skelly, J V, Hudson, B D, Neidle, S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1987
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340742/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3575097/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.8.3469
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