Crystal structure of a berenil-dodecanucleotide complex: the role of water in sequence-specific ligand binding.

The three-dimensional structure of a complex between the dodecanucleotide d(CGCGAATTCGCG) and the anti-trypanocidal drug berenil, has been determined to a resolution of 2.5 A. The structure has been solved by molecular replacement and refined to an R factor of 0.177. A total of 49 water molecules ha...

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Detalhes bibliográficos
Main Authors: Brown, D G, Sanderson, M R, Skelly, J V, Jenkins, T C, Brown, T, Garman, E, Stuart, D I, Neidle, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC551811/
https://ncbi.nlm.nih.gov/pubmed/2323343
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