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The crystal structure of the DNA-binding drug berenil: molecular modelling studies of berenil-DNA complexes.

The crystal structure of the DNA minor-groove DNA-binding drug berenil has been determined. Molecular-modelling techniques have been used to establish plausible binding modes of the structure to A-T sequences. These have shown that specific hydrogen bonds are possible between the amidine groups of t...

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Bibliografske podrobnosti
Main Authors: Pearl, L H, Skelly, J V, Hudson, B D, Neidle, S
Format: Artigo
Jezik:Inglês
Izdano: 1987
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC340742/
https://ncbi.nlm.nih.gov/pubmed/3575097
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