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Integrative Gene Expression Profiling Reveals G6PD-Mediated Resistance to RNA-Directed Nucleoside Analogues in B-Cell Neoplasms

The nucleoside analogues 8-amino-adenosine and 8-chloro-adenosine have been investigated in the context of B-lineage lymphoid malignancies by our laboratories due to the selective cytotoxicity they exhibit toward multiple myeloma (MM), chronic lymphocytic leukemia (CLL), and mantle cell lymphoma (MC...

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Autors principals: McBrayer, Samuel K., Yarrington, Michael, Qian, Jun, Feng, Gang, Shanmugam, Mala, Gandhi, Varsha, Krett, Nancy L., Rosen, Steven T.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407247/
https://ncbi.nlm.nih.gov/pubmed/22848499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041455
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