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Fbxw7 Controls Angiogenesis by Regulating Endothelial Notch Activity

Notch signaling controls fundamental aspects of angiogenic blood vessel growth including the selection of sprouting tip cells, endothelial proliferation and arterial differentiation. The E3 ubiquitin ligase Fbxw7 is part of the SCF protein complex responsible for the polyubiquitination and thereby p...

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Detalles Bibliográficos
Main Authors: Izumi, Nanae, Helker, Christian, Ehling, Manuel, Behrens, Axel, Herzog, Wiebke, Adams, Ralf H.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407154/
https://ncbi.nlm.nih.gov/pubmed/22848434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041116
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