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Fbxw7 regulates Notch to control specification of neural precursors for oligodendrocyte fate

BACKGROUND: In the developing vertebrate nervous system elevated levels of Notch signaling activity can block neurogenesis and promote formation of glial cells. The mechanisms that limit Notch activity to balance formation of neurons and glia from neural precursors are poorly understood. RESULTS: By...

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Autori principali: Snyder, Julia L, Kearns, Christina A, Appel, Bruce
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404928/
https://ncbi.nlm.nih.gov/pubmed/22554084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-7-15
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