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Fbxw7 Controls Angiogenesis by Regulating Endothelial Notch Activity
Notch signaling controls fundamental aspects of angiogenic blood vessel growth including the selection of sprouting tip cells, endothelial proliferation and arterial differentiation. The E3 ubiquitin ligase Fbxw7 is part of the SCF protein complex responsible for the polyubiquitination and thereby p...
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Auteurs principaux: | , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Public Library of Science
2012
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407154/ https://ncbi.nlm.nih.gov/pubmed/22848434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041116 |
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