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Fbxw7 Controls Angiogenesis by Regulating Endothelial Notch Activity

Notch signaling controls fundamental aspects of angiogenic blood vessel growth including the selection of sprouting tip cells, endothelial proliferation and arterial differentiation. The E3 ubiquitin ligase Fbxw7 is part of the SCF protein complex responsible for the polyubiquitination and thereby p...

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Détails bibliographiques
Auteurs principaux: Izumi, Nanae, Helker, Christian, Ehling, Manuel, Behrens, Axel, Herzog, Wiebke, Adams, Ralf H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407154/
https://ncbi.nlm.nih.gov/pubmed/22848434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041116
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